Exploration of pan-genome and small proteins in Staphylococcus

Methicillin resistant Staphylococcus aureus (MRSA) is Staphylococcus aureus strain that causes community-acquired as well as nosocomial infections and it is resistant to some antibiotics. MRSA strain leads to the life-threatening infections in the countries having maintenance systems along with advanced health surveillance. MRSA’s incidence rate has enhanced histrionically and has been associated with infections of wound establishing considerable sources of the rate of high morbidity as well as mortality. Such development of the resistant strains is because of overdoing undeveloped antibiotics that eventually makes real tests at treatment. Antibiotic resistance can be because of overuse/misuse of prescribed antibiotics as well as recent existing antibiotic’s limitation. Progressive intensification of antibiotic resistance in MRSA has ensued restricted option for the treatment. So, there is a crucial necessity to discover the resistance mechanism’s genetic basis for improved understanding as well as addressing probable effective targets of drug.