Application of bio printing

1)Tissue engineering and regenerative medicine:It’s still a big challenge to bioprint functional organs

at sizes that are useful in medical practice. One of the main obstacles is figuring out how to integrate

the blood vessels, from the big arteries and veins all the way down to the tiny capillaries. Another

hurdle is making sure we include all the different types of cells that make up an organ, so that it

functions properly. On top of that, we also need to address the issues of structural strength and longterm functionality. These are just a few of the many challenges we face in the field of bioprinting

organs.There are many tissues are bioprinted overcoming this challenges.

2)Transplantation and clinics:

The field of bioprinting living tissue and organ constructs has been extensively researched, with the

effectiveness of these constructs being evaluated through animal transplantation. Different types of

bioprinted tissues such as skin blood vessels etc ,have been implanted in specific areas of animals to

assess their functionality, neovascularization, anastomosis, and integration with the host .

Furthermore, various tissue constructs have been bioprinted and successfully implanted.

3)Pharmaceutics and high-throughput screening:Drug discovery is a lengthy and expensive process

that demands significant investments in both money and manpower. Despite ongoing attempts to

enhance the efficiency of drug development, only a small fraction of new chemical entities and drug

candidates make it through clinical trials and receive final approval. This highlights the need to

improve our ability to forecast the effectiveness and safety of potential drugs at an earlier stage. This

can be done using bioprinting.

4)Cancer research:Two-dimensional tumor models have been extensively utilized in cancer research.

However, they fail to accurately mimic the physiologically relevant environment due to the absence

of cell-cell and cell-matrix interactions in three dimensions. As a result, bioprinting has emerged as a

promising technique to recreate the cancer microenvironment. It enables precise placement of

different cell types and microcapillaries, facilitating the study of cancer pathogenesis and metastasis.

Despite its potential, bioprinting for cancer research is still in its early stages, with only a limited

number of research procedures conducted so far.