Mechanisms of Neuroplasticity: Neuroplasticity is achieved through several mechanisms, including changes in synaptic strength, dendritic branching, and the formation of new synapses. Synaptic plasticity, the ability of synapses to change in strength and efficacy, is one of the most important mechanisms of neuroplasticity. Synaptic plasticity is mediated by several neurotransmitters, including glutamate, dopamine, and serotonin.