Article

6-2018

Systematic review written for the Master of Science in Occupational Therapy class Critical Inquiry I & Critical Inquiry II.

Sensory-based treatment methods are commonly used by occupational therapists and others working with individual with ADHD and ASD (Wan Yunus, Liu, Bissett, & Penkala, 2015). Weighted vests or weighted blankets are popular sensory-based interventions used with people with these conditions. Weighted vests and weighted blankets are widely reported to have various benefits and positive outcomes with children with these conditions (Shulman, 2018). They are thought of as providing deep pressure that is reported to help clients self-regulate, diminish episodes of maladaptive behavior and anxiety or stress, and improve attention, sleep, and mood (Shulman, 2018). A series of systematic reviews have previously been performed to assess the level and quality of evidence of the available literature regarding weighted vests and weighted blankets. These previous reviews have all concluded that weighted vests and weighted blankets did not have efficacy and that limited evidence currently exists that examines weighted vests and weighted blankets (Case-Smith, Weaver, & Fristad, 2014; Taylor, Spriggs, Jones Ault, Flanagan, & Sartini, 2017; Wan Yunus, Liu, Bissett, & Penkala, 2015; Watling & Hauer, 2015). Additionally, all four of these systematic reviews were of high quality of evidence (Case- Smith, Weaver, & Fristad, 2014; Taylor, Spriggs, Jones Ault, Flanagan, & Sartini, 2017; Wan Yunus, Liu, Bissett, & Penkala, 2015; Watling & Hauer, 2015). However, these systematic reviews focused on one specific population or one specific outcome, a more general systematic review to understand the overall efficacy of weighted vests and blankets has yet to be completed. To fill this gap, a systematic review was conducted to answer the following question: To what degree are weighted vests and weighted blankets efficacious when utilized for people with ASD or ADHD?

Denny, E.; Folkes, W.; Ghattas, I.; Kaufmann, H.; Williams, H.; and Potvin, Marie-Christine, "A Systematic Review of the Efficacy of Weighted Vests and Blankets on People with ASD or ADHD" (2018). Student Papers, Posters & Projects. Paper 20. https://jdc.jefferson.edu/student_papers/20

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This article has been peer reviewed. It is the author’s final published version in JAAD Case Reports, Volume 4, Issue 6, July 2018, Pages 584-585.

The published version is available at https://doi.org/10.1016/j.jdcr.2018.03.009. Copyright © Gaffney et al.

Here we describe a caseof a woman who had DM after treatment withlacosamide. To our knowledge, drug-induced DMfrom lacosamide has not been reported previously.

Gaffney, Rebecca G.; Tarazi, Meera; and Werth, Victoria P., "Drug-induced dermatomyositis after lacosamide: A case report." (2018). Student Papers, Posters & Projects. Paper 37. https://jdc.jefferson.edu/student_papers/37

This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

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This article has been peer reviewed. It is the author’s final published version in Evidence-based Complementary and Alternative Medicine, Volume 2018 May 2018, Article number 4505191.

The published version is available at https://doi.org/10.1155/2018/4505191. Copyright © Greeson et al.

Mindfulness-Based Stress Reduction (MBSR) is an 8-week meditation program known to improve anxiety, depression, and psychological well-being. Other health-related effects, such as sleep quality, are less well established, as are the psychological processes associated with therapeutic change. This prospective, observational study (

Greeson, Jeffrey M.; Zarrin, Haley; Smoski, Moria J.; Brantley, Jeffrey G.; Lynch, Thomas R.; Webber, Daniel M.; Hall, Martica H.; Suarez, Edward C.; and Wolever, Ruth Q., "Mindfulness Meditation Targets Transdiagnostic Symptoms Implicated in Stress-Related Disorders: Understanding Relationships between Changes in Mindfulness, Sleep Quality, and Physical Symptoms." (2018). Student Papers, Posters & Projects. Paper 14. https://jdc.jefferson.edu/student_papers/14

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This article has been peer reviewed. It is the author’s final published version in Oncotarget, Volume 9, Issue 72, September 2018, Pages 33623-33633.

The published version is available at https://doi.org/10.18632/oncotarget.25890. Copyright © Hafazalla et al.

Low-grade gliomas (LGG) encompass a heterogeneous group of tumors that are clinically, histologically and molecularly diverse. Treatment decisions for patients with LGG are directed toward improving upon the natural history while limiting treatment-associated toxiceffects. Recent evidence has documented a utility for adjuvant chemotherapy with procarbazine, CCNU (lomustine), and vincristine (PCV) or temozolomide (TMZ). We sought to determine the comparative utility of PCV and TMZ for patients with LGG, particularly in context of molecular subtype. A literature search of PubMed was conducted to identify studies reporting patient response to PCV, TMZ, or a combination of chemotherapy and radiation therapy (RT). Eligibility criteria included patients 16 years of age and older, notation of LGG subtype, and report of progression-free survival (PFS), overall survival (OS), and treatment course. Level I, II, and III data were included. Adjuvant therapy with PCV resulted in prolonged PFS and OS in patients with newly diagnosed high-risk LGG. This benefit was accrued most significantly by patients with tumors harboring 1p/19q codeletion and IDH1 mutation. Adjuvant therapy with temozolomide was associated with lower toxicity than therapy with PCV. In patients with LGG with an unfavorable natural history, such as with intact 1p/19q and wild-type IDH1, RT/TMZ plus adjuvant TMZ may be the best option. Patients with biologically favorable high-risk LGG are likely to derive the most benefit from RT and adjuvant PCV.

Hafazalla, Karim; Sahgal, Arjun; Jaja, Blessing; Perry, James R; and Das, Sunit, "Procarbazine, CCNU and vincristine (PCV) versus temozolomide chemotherapy for patients with low-grade glioma: a systematic review." (2018). Student Papers, Posters & Projects. Paper 16. https://jdc.jefferson.edu/student_papers/16

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