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A productized service for pharma medicinal-chemistry teams that converts
literature and curated databases into a structured, source-traced SAR
landscape — in 24 hours, at a fraction of the cost of an analyst.
What you get
Structured dataset of compounds (canonical SMILES, Bemis–Murcko scaffold, MW / cLogP / TPSA / HBD / HBA descriptors, server-rendered SVG structures)
Bioactivity table (IC50, Ki, EC50, Kd) with values normalised to nM
Author-stated SAR claims and trends, each anchored to a verbatim snippet
Every fact carries a source pointer: paper / patent / database, section, quoted text — pharma compliance and IP teams require this
CSV export, with PDF report packaging available on request
The network for creativity
Join 1.25M professional creatives like you
Connect with clients, get discovered, and run your business 100% commission-free
Creatives on Contra have earned over $150M and we are just getting started
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Is motion on a pricing page persuasive or distracting?
Genuinely don't know. Built one to find out.
I use Claude every day
I think I'm pretty good at it
I watch two Anthropic engineers for 2 HOURS
Claude's engineer explains Skills from scratch
the first 5 minutes
wait. Skills are just folders?
folders that hold onto your workflow?
your domain? your expertise?
pause. rewind. I watch again
I think about every prompt I've rewritten from scratch
every context I've explained 100 times
every session that forgot everything
this shouldn't have happened like that
16 minutes. everything changes
skill issue detected:
is there a video? can you share the link to it? i'd like to watch
PROJECT NAME
AION PYR — The Aitherioi
CONCEPT / PROJECT DESCRIPTION
AION PYR is a one-minute instrumental progressive-rock film by The Aitherioi, a fictional trio of pale pre-terrestrial beings older than Earth.
They were here when the planet was born from heat, basalt, and lava, and they remain calm as that world dissolves into stardust. The film follows them performing inside a collapsing volcanic cathedral while lava, steam, lightning, and stone slowly give way to void.
The music is built only from guitar, bass, and drums: slow, heavy, repetitive, bass-led, and cathartic.
PROCESS
I started by defining The Aitherioi: a fictional pre-terrestrial trio with a shared visual identity, pale ethereal bodies, severe faces, long dark hair, and calm expressions.
Then I built the visual system around contrast: fossil-dark basalt, living lava, white steam, lightning, and their stillness inside collapse.
I created character assets, face studies, wardrobe references, instrument references, environment plates, keyframes, and individual video scenes.
The music was built first as a strict one-minute instrumental progressive-rock track using only guitar, bass, and drums. The video was then structured to follow the track: bass opening, wide trio, basalt corridor, guitar catharsis, drummer pulse, matter dissolution, and final void.
Finally, I stitched the scenes together with clean cuts so the film follows the music without extra transitions or title cards.
FEEDBACK ON BUILDING WITH MELIUS
Melius worked best as a production canvas rather than a single-prompt generator.
The node-based workflow made it possible to build the project in layers: character identity, environments, audio, keyframes, video clips, and final assembly. That helped keep the concept coherent while still allowing corrections when individual shots needed refinement.
The biggest challenge was visual continuity, especially keeping The Aitherioi consistent across scenes. The most useful approach was creating strict reference assets first, then using them as anchors for keyframes and video generation.
This is raw power, like it so much!
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